Arsenic Poisoning in Dogs

Arsenic Intoxication in Dogs

Arsenic is a heavy metal mineral that is commonly included in chemical compounds for consumer products, such as herbicides (chemicals to kill unwanted plants), insecticides (chemicals to kill insects), wood preservatives, and in some drug formulas for treating blood parasites like heartworm. In parasitic treatment drugs, the level of arsenic is in sub-lethal ranges and will not harm a dog, but over-dosage can lead to toxicity. In most cases, dogs accidentally ingest products containing arsenic when they gain access to such compounds.

Symptoms and Types


In case of acute exposure to arsenic, the following symptoms may be present in an affected dog:

• Vomiting
• Diarrhea
• Abdominal pain
• Lethargy
• Staggering
• Fresh bright red blood in feces
• Lying down with extreme exhaustion
• Body may feel unusually cold especially at extremities including ear, and limb extremities
• Loss of consciousness
• Death in untreated dogs, or in cases of heavy intoxication
• In chronic (long-term) exposure symptoms may be subtle like poor appetite and weight loss

Causes

• Ingestion of arsenic-containing compounds
• Overdose of arsenic-containing drugs to treat heartworm parasites in dogs

Diagnosis

Background history is very important in the diagnosis of arsenic poisoning and your veterinarian will need to know about any arsenic-containing compounds you have at home. You will need to give a thorough history of your dog's health, onset of symptoms, and possible incidents that might have precipitated this condition. A history of any medications given to your dog lately will also help in diagnosis. Frequently, owners will bring their dogs to the veterinarian with the complaint of a sudden unexplained episode of vomiting. However, few owners report seeing their dogs ingest arsenic-containing compounds so this may not be the first cause that apparent. Your veterinarian will perform a complete blood profile, including a chemical blood profile, a complete blood count, and a urinalysis. A sample of the stomach contents may also be necessary. Arsenic in the blood stream or stomach contents will confirm the diagnosis. In cases of chronic arsenic poisoning the level of arsenic in the body can be evaluated from a hair sample, as arsenic is deposited in the hair over a course of time.

If possible, you should collect a sample of the vomit or diarrhea to take to the veterinarian. This will help to speed the diagnostic process so that your dog can be treated before further damage is done.

Treatment

Acute (sudden) arsenic poisoning is an emergency and time remains the crucial factor for a successful outcome. Vomiting plays a protective role in arsenic poisoning as it expels a large portion of the ingested poisonous material. However, if vomiting is not initiated in the immediate aftermath, your veterinarian will need to perform a gastric lavage (stomach irrigation) to wash out the stomach contents. As arsenic severely damages the liver and kidneys, dialysis is conducted for dogs that are in a state of kidney failure due to arsenic poisoning. The main objective of treatment is to flush the poison out of the body; therefore fluid therapy and drugs promoting excretion are commonly employed. Also, some compounds are known to chelate (bind) heavy metals such as arsenic, and are commonly used to bind arsenic that is still present in the body. Chelators work both by slowing the arsenic down before it can cross the blood-brain barrier, and by making it more water-soluble so that it can be washed from the body more effectively. Your veterinarian can employ such antidotes to enhance recovery in your dog. Your dog may need to be admitted into the veterinary hospital for a few days until it has stabilized and is completely out of danger.

Conversely, if you actually witnessed your dog consuming the poison, you can act quickly by inducing vomiting, but this must be done immediately following the event. Call your doctor for instructions on how to induce vomiting safely. If time elapses from the time of ingestion, only a veterinarian can treat your dog. Because induced vomiting can be dangerous with some toxins, as some poisons will do more harm coming back through the esophagus than they did going down, do not induce vomiting unless you are absolutely sure of what your dog has ingested. If your dog has already vomited, do not try to force more vomiting. 

A final word, do not induce vomiting if your dog is unconscious, is having trouble breathing, or is exhibiting signs of serious distress or shock. Whether your dog vomits or not, after the initial care, you must take it to a veterinary facility immediately.

Living and Management

After returning from the hospital, allow your dog proper rest and protect it from any source of stress. Follow your veterinarian’s guidelines for home treatment, such as medication and nutrition. Easily digestible food is often recommended for dogs that are recovering from a poisoning.

Ensure that all sources of arsenic-compounds are secured or removed. If they must be kept in the home, be sure that they are out of reach of children and pets. Most problems are easily avoided if guidelines for handling and keeping such poisonous compounds are followed.

Keep an eye on your dog and if you observe anything unusual in its behavior, immediately consult your veterinarian. Unfortunately, in many cases of heavy intoxication, very few patients survive unless treatment is started very early.