Methyl Prednisolone

PetMD Editorial

. Medically reviewed by

Carina Fung, PharmD, MBA, BCPPS

Published Nov. 7, 2012

Drug Info

Common Name: Medrol®, Depo-Medrol®
Drug Type: Corticosteroid
Used For: Severe inflammation
Species: Dogs, Cats
Administered: Tablets, injectable
FDA Approved: Yes

General Description

Methyl prednisolone is a short-acting anti-inflammatory drug related to prednisone. It reduces severe inflammation and suppresses the immune system. It can be beneficial in treating many diseases and disorders, but should be given at low doses for short period of time to reduce any adverse effects. They may also be used to assist in treatment of allergies, arthritis, asthma, colitis, Addison’s disease, auto-immune skin disorders, and certain forms of kidney disease. It may also be used in conjunction with other drugs to treat brain and spinal cord injuries.

Unlike prednisone, Methyl Prednisolone comes in a one-time injectable form, Depo-Medrol. This is extremely useful in cats and pets that are difficult to pill.

How It Works

Methyl prednisolone is a corticosteroid known as a glucocorticoid. Corticosteroids are meant to resemble a naturally occurring hormone produced in the adrenal cortex, cortisol. Corticosteroids act on the immune system by blocking the production of substances that trigger inflammatory and immune responses.

Storage Information

Store in a tightly sealed container at room temperature.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.