12 Signs of Cancer in Dogs

Updated Apr. 1, 2025
signs of cancer in dogs: lethargic dog lying on couch

SolStock/iStock/Getty Images Plus via Getty Images

Nobody likes to hear the word cancer, and unfortunately this disease is common in dogs, especially those of senior age. The signs of cancer in dogs can be subtle and easy to overlook, but pet parents can use this guide to learn what to look for.  

Early detection and treatment of cancer in dogs is critical. By detecting cancer early, you and your veterinarian can determine a suitable treatment approach to increase the chance for cure or remission.  

If you notice any unusual symptoms in your dog, consult your veterinarian as soon as possible. 

12 Signs of Cancer in Dogs

Various signs a dog could have cancer range from subtle abnormalities to obvious symptoms.  

It’s important to recognize that each dog may experience varying symptoms depending on the type of cancer they have, and that cancer symptoms in dogs are often subtle, especially early on. 

The most common signs of cancer in a dog include:  

1. Unexplained Weight Loss 

  • Why it’s a concern: Sudden weight loss can be an early sign of cancer, especially in the digestive system. 

2. Changes in Appetite 

  • What it may indicate: gastrointestinal tumors, lymphoma, oral melanoma 

3. Gastrointestinal Upset 

  • What it may indicate: gastrointestinal tumors, lymphoma, liver cancer 

4. Lethargy  

  • Why it’s a concern: Extreme lethargy may indicate underlying cancer because tumors take a lot of energy to grow. Blood cells may also be negatively impacted by cancer, resulting in lethargy.  

5. Enlarged Lymph Nodes 

  • Why it’s a concern: Swollen lymph nodes can occur directly as a result of cancer or due to metastasis (spread) of cancer throughout the body.  

6. Skin Lumps 

  • Why it’s a concern: When dogs develop lumps on their skin, especially if they grow rapidly or are irregular in appearance or size, they should be checked for cancer.  

7. Pain or Swelling  

  • What it may indicate: Osteosarcoma, hemangiosarcoma, soft tissue sarcoma  

8. Difficulty Breathing or Coughing  

  • Why it’s a concern: Dogs may have difficulty breathing or experience frequent coughing episodes if a tumor is within or putting pressure on their airways.  

  • What it may indicate: Lymphoma, lung cancer, hemangiosarcoma 

9. Body Odor  

  • Why it’s a concern: Dogs with cancer often have abnormal body odors, such as bad breath, due to tumors and the compounds they release in the body.  

10. Abnormal Bleeding 

  • Why it’s a concern: Some types of cancers interfere with or damage blood vessels, which can result in bleeding from the nose and mouth or internal bleeding.  

  • What it may indicate: Hemangiosarcoma, oral cancer, lymphoma 

11. Impaired Wound Healing  

  • Why it’s a concern: Cancer can disrupt a dog’s normal immune function, thereby disrupting normal wound healing.  

  • What it may indicate: Mast cell tumors, skin cancer, hemangiosarcoma 

12. Urinary Changes  

How To Help Detect Cancer in Dogs Early

Pet parents can take steps to help detect cancer early in their pets. Here are helpful tips: 

Seek Regular Preventative Veterinary Care 

One of the most important steps you can do to identify health problems, such as cancer, is to bring your pet to see a veterinarian for regular checkups. Any obvious abnormalities like skin lumps or concerning symptoms can be addressed.  

Adult dogs should visit the veterinarian at least once per year, and senior dogs should be seen twice yearly.  

Do Routine Bloodwork and Urinalysis 

Be proactive about your dog’s health by agreeing to lab work, including blood work and a urinalysis, at your dog’s wellness checkups.  

These are vital tests that give veterinarians insight into a dog’s overall health.  

Inspect Their Tongue and Oral Cavity 

Hold a yummy dog treat out and let your pet lick the treat while you visually inspect the top and bottom of their tongue.  

Certain types of cancer, such as squamous cell carcinoma, can affect the tongue and other parts of the oral cavity.  

Never reach your hands inside your dog’s mouth or try to pry it open to inspect, as this can be a bite risk.  

Feel Their Skin and Coat 

Gently rub your hands along your dog’s skin and coat to feel for any new lumps or bumps that have developed.  

Take note of any wounds that don’t appear to be healing well.  

Inspect Their Body, Face, and Paws 

Identify if your pet has lost weight. Visually inspect your dog’s face and paws for obvious abnormalities, such as abnormal bleeding or wounds. 

Feel Their Leg Bones and Joints 

Gently run your hands down your dog’s leg to identify any obvious swelling or discomfort.  

Osteosarcoma is a common bone cancer that affects dog legs.  

Pay Attention To Subtle Changes in Your Dog’s Behavior 

If your dog seems more tired than normal or their food bowl is left untouched, it could indicate an underlying issue that needs to be addressed.  

Likewise, changes in urinary habits should not be ignored.  

Dog Cancer Symptoms FAQs

What are the first signs of cancer in dogs?

Depending on the type of cancer, there may be very minimal early signs. Dogs may experience reduced appetite, vomiting, weight loss, or obvious lumps on their skin. 

How can I tell if my dog’s lump is cancerous?

The only way to tell if a dog’s lump is cancerous is to schedule a veterinary checkup where a veterinarian will take a sample of the lump and view it under the microscope and possibly send it to a pathology lab.  

Unfortunately, the appearance and the feeling of lumps does not determine whether they are benign or cancerous.  

How common is cancer in dogs?

Cancer is very common in dogs, especially those of senior age. It is estimated that 25% of all dogs (and 50% of senior dogs) will develop cancer in their lives. 

What is the most common cancer in dogs?

Several cancers are common in dogs, but lymphoma is one of the most prevalent.  

References

1. Cancer in Pets | American Veterinary Medical Association 

References


Brittany Kleszynski, DVM

WRITTEN BY

Brittany Kleszynski, DVM

Veterinarian

Dr. Brittany Kleszynski is a veterinarian and freelance medical writer who specializes in creating meaningful content that engages readers...


Help us make PetMD better

Was this article helpful?


Get Instant Vet Help Via Chat or Video. Connect with a Vet. Chewy Health