Degeneration of the Cerebellum of the Brain in Dogs

Cerebellar Degeneration in Dogs

Cerebellar degeneration in dogs is a brain disease. As its name suggests, it affects a specific area of the brain known as the cerebellum. In cerebellar degeneration, the cells within the cerebellum die, causing neurological symptoms in the dog.

Symptoms and Types

Symptoms of cerebellar degeneration in dogs include:

• An abnormal gait which often appears as a goose-step involving the front legs
• A broad-based stance
• Swaying
• Muscle tremors, especially when trying to eat or perform another activity
• Normal vision with no menace reflex
• Head tilt
• Loss of coordination (vestibular ataxia)
• Normal mental activity
• Abnormal posturing with head back, front legs rigid and hind legs flexed (decerebellate posture)
• Progression of symptoms may or may not occur

Causes

Infection with canine herpesvirus either in utero or as a neonate may cause cerebellar degeneration in dogs. A genetic predisposition for the condition is possible in some dog breeds, including Irish setters, wire-haired fox terriers, Samoyeds, chow chows, rough-coated collies, border collies, bullmastiffs, Labrador retrievers, beagles, Kerry blue terriers, Finnish harriers, Bern running dogs, English pointers, Gordon setters, Brittany spaniels, American Staffordshire terriers and English bulldogs.

Diagnosis

MRI (magnetic resonance imaging) may reveal a smaller than normal cerebellum. Cerebrospinal fluid analysis may be normal or abnormal depending on the individual cause. Biopsy of the cerebellum is the definitive means of diagnosis.

Routine blood and urine testing may be necessary to rule out other disease conditions which may appear similar.

Treatment

There is no curative treatment, though medications such as amantidine, buspirone, co-enzyme Q10, and acetyl-l-carnitine have shown some promise.

Living and Management

This type of brain disease in dogs can lead to poor coordination and decision making by the dog. Restrict the dog’s activity to safe areas of the household where it cannot be injured. Avoid stairs, sharp objects, swimming pools, and other dangers that could harm the dog.

Because of the loss of coordination, dogs with cerebellar degeneration may require physical aid in eating, though they can continue to eat a normal diet. Nursing care to keep the pet free of urine and feces may also be necessary.