Diarrhea Due to Clostridium perfringens in Cats

Clostridial Enterotoxicosis in Cats

Clostridium perfringens bacterium is a normal bacteria found in the environment, commonly inhabiting decaying vegetation and marine sediment, as well as raw or improperly cooked meats and poultry. However, when abnormally high levels of this bacteria is found in the intestine, it can lead to Clostridial enterotoxicosis.

Generally, the implications of the intestinal syndrome are limited to infections of the intestinal tract and do not progress to systemic disease conditions. Symptoms typically last a week in acute cases and include diarrhea, abdominal pain, and nausea. Long-term (chronic) cases of clostridial enterotoxicosis, meanwhile, involve recurrences of diarrhea, which may repeat every two to four weeks, and may continue for months to years.

When compared to its incidence in dogs, this is an uncommon condition in cats. Most animals have antibodies that will effectively fight the bacteria and clear it from the body.

Symptoms and Types

• Diarrhea with shiny mucus on its surface
• Small amounts of fresh blood in diarrhea
• Small, meager stools
• May have large volume of watery stools
• Straining to defecate
• Increased frequency of defecation
• Vomiting (on occasion)
• Abdominal discomfort – characterized by standing with lowered front and raised back end, or curling up to cover abdomen, resistant to being touched in abdominal area
• Abnormal amount of flatulence (i.e, passing gas)
• Fever (uncommon)

Causes

Clostridial enterotoxicosis is caused by an overgrowth of the bacteria Clostridium perfringens in the intestine. Often, the bacteria is acquired from the environment (e.g., flora) or as the result of eating raw, undercooked, or old meat. Other risk factors include:

• Dietary changes
• Abnormally high pH level in the intestine
• Deficiency of antibodies
• Exposure to other cats at a hospital or kennel
• Stress to the digestive system due to concurrent disease (e.g., parvovirus, gastroenteritis, and inflammatory bowel disease)

Diagnosis

You will need to give a thorough history of your cat's health, onset of symptoms, and possible incidents that might have precipitated/preceded this condition, such as time spent outdoors, rummaging through garbage or getting hold of old or uncooked meat, or being boarded at a kennel.

Your veterinarian will conduct a thorough physical exam on your cat as well as standard blood work, including a complete blood count, chemical blood profile, and urinalysis. Most of these tests will return normal. Because this infection has obvious intestinal symptoms, a fecal sample will need to be taken for microscopic analysis.

This intestinal disease is sometimes difficult to identify because there is no one good test for it. Often, false positive results will return as the result of interfering substances in the feces. Your veterinarian may also want to use an endoscope to visualize the interior of your cat's intestines, and possibly take a tissue sample.

Treatment

Treatment is generally simple, with outpatient care provided until your cat has recovered from the infection. In some cases, when diarrhea and/or vomiting has been severe and the animal has become dehydrated and low in electrolytes, fluid therapy will need to be administered in a hospital setting.

Your veterinarian may prescribe a week’s worth of oral antibiotics if the Clostridium perfringens toxin is found. Cats that need to be treated for long-term cases of diarrhea may need to be given antibiotics for a longer period of time.

Dietary management is also helpful in the treatment of this condition. High-fiber diets and diets formulated with prebiotic and probiotic ingredients (like lactobacillus) can help to balance and maintain the intestinal flora of the gastrointestinal tract. 

Living and Management

This disease is treated and managed in long-term cases by switching your pet to a high in fiber diet, which reduces Clostridium perfringens and enterotoxin production in the intestinal tract. Your veterinarian might also recommend that you supplement your cat's diet with psyllium, a soluble source of fiber. Prebiotic and probiotic diets might also be recommended by your veterinarian in order to try to maintain the normal balance of good bacteria in your cat's intestine.

Fortunately, cats with good immune response will generally fight off the infection easily.